Mark Nachtigal is a Professor in the Departments of Biochemistry & Medical Genetics, and Obstetrics, Gynecology, and Reproductive Sciences and a Senior Scientist in the CancerCare Manitoba Research Institute. He received his B.Sc. and Ph.D. (Molecular Endocrinology) degrees from the University of Manitoba and conducted post-doctoral research at the University of California San Francisco, Reproductive Endocrinology Centre. Throughout his graduate and post-graduate training his research projects retained a link to human reproductive cancer biology. In 1998 Dr. Nachtigal was recruited to Dalhousie University as theRossetti Scholar for Cancer Research to study human epithelial ovarian cancer. Dr. Nachtigal returned to Manitoba in 2010 to continue his research on human ovarian cancer. His first contributions in Manitoba were the establishment of the Manitoba Ovarian Biobank Program in collaboration with the Manitoba Tumor Bank, and establishing the Manitoba Ovarian Cancer Outcomes (MOCO) study group in partnership with Gynecologic Oncology and Population Oncology. Further collaborations led to the Manitoba Ovarian Cancer Research (MOCR) Program that encompasses researchers from preclinical, translational, clinical and health outcomes disciplines. His preclinical and translational research has established methods for culturing primary human ovarian cancer cells, identified novel autocrine signaling pathways that maintain cancer cell plasticity, developing new genetic models of early changes leading to high grade serous ovarian cancer, and testing novel therapeutics in ovarian cancer models.